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名称: 内消旋-2,3-二巯基丁二酸英文名称: meso-2,3-Dimercaptosuccinic acid98%产品编号 D107254
CAS号: 304-55-2分子式 C4H6O4S2分子量182.22
Beilstein号 1725150EC号 206-155-2MDL号 MFCD00064799PubChem编号 24894166
安全声明(欧洲) | S24/25 |
个人防护设备 | Eyeshields,Gloves,type N95 (US),type P1 (EN143) respirator filter |
WGK德国 | 2 |
密度 | 1.6170 |
熔点 | 196-198°C |
溶解性 | Soluble in water, and ethanol (25 mg/ml, Colorless to Light Yellow, Clear). |
存贮条件 | 储存温度-20°C |
产品介绍 | DMSA (Meso-2,3-dimercaptosuccinic acid) is a potent lead chelating agent found to be a scavenger of reactive oxygen species (ROS). Murine experiments have shown that this compound also lowers blood pressure in rat arterial hypertension via a decrease in total cell calcium levels. It has also been observed that DMSA upregulates mRNA expression of macrophage-1 antigen, L-, E-, and P-selectin, as well as causing an increase in TNFα (tumor necrosis factor-α) concentrations in murine lung. Mechanistic studies suggest that DMSA is metabolized into mixed disulfides of cysteine, which are active chelating agents. |
别名 | 2,3-二硫代-内消旋酒石酸;DIM-SA;DMS;DMSA;二巯基丁二酸;间-2,3-二巯基丁二酸;2,3-Dithio-meso-tartaric acid; DIM-SA;DMS;DMSA;Succimer |
应用 | A water-soluble chelating agent. |
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