52665-69-7钙离子载体 A23187

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商品编号：C137844

库存现货：9

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商品名称：52665-69-7钙离子载体 A23187
商品毛重：0.00
单位：件
上架时间：2017-11-01 20:36:21

名称: 钙离子载体 A23187英文名称: Calcium Ionophore A23187≥97%产品编号 C137844
CAS号: 52665-69-7分子式 C₂₉H₃₇N₃O₆分子量523.62
Beilstein号 EC号 MDL号 PubChem编号

属性

敏感性	对光敏感
溶解性	Soluble in water (Partly miscible), DMSO (1 mg/ml), and DMF (10 mg/ml).
存贮条件	储存温度2-8℃

描述

产品介绍	A23187 is an ionophore, highly selective for Ca2+, that allows for divalent cations to move across the membranes which are usually impermeable to them. The compound was originally isolated from Streptomyces chartreusensis for use as an antibiotic but has been shown to have weak in vitro antimicrobial activity against fungi and gram positive bacteria. Because of its ability to increase intracellular calcium levels of intact cells, it is used in studies of intracellular Ca2+ mediated events. A23187 has been observed to induce cell activation, differentiation or proliferation. In vitro experimentation has shown A23187 to boost ROS generation and platelet fragmentation
别名	A23187 ;抗生素 A 23187 ;钙离子载体;Antibiotic A 23187 ;Calimycin;A23187
应用	高选择性钙离子载体增强对 NMDA 非使君子氨酸的响应。在细胞培养中，通过钙调素依赖结构型一氧化氮合酶刺激一氧化氮的生成。