79831-76-8栗精胺

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  • 商品名称:79831-76-8栗精胺
  • 商品毛重:
  • 单位:件
  • 上架时间:2017-11-01 18:39:47

名称: 栗精胺英文名称: Castanospermine98%产品编号 C130954
CAS号: 79831-76-8分子式 C8H15NO4分子量189.21
Beilstein号 3588654EC号 MDL号 MFCD00017555PubChem编号 24892642

标识符号 GHS07GHS07
信号词 Warning
警示性声明 P280
危害声明 H302-H312-H332
个人防护设备 dust mask type N95 (US), Eyeshields, Gloves
WGK德国 3

属性

溶解性 Soluble in 1N HCl (20 mg/ml, yielding a clear, colorless to faint yellow solution), and DMSO (75 mM). Insoluble in water.
存贮条件 储存温度 2-8°C

描述

别名 (1S,6S,7R,8R,8aR)-1,6,7,8-四羟基八氢吲哚里西定;(1S,6S,7R,8R,8aR)-八氢-1,6,7,8-吲嗪四醇; 1,6,7,8-四羟基八氢吲嗪;(1S,6S,7R,8R,8aR)-1,2,3,5,6,7,8,8a-八氢吲嗪-1,6,7,8-四醇;栗树精胺;(1S,6S,7R,8R,8aR)-1,6,7,8-Tetrahydroxyoctahydroindolizidine; (1S,6S,7R,8R,8aR)-Octahydro-1,6,7,8-indolizinetetrol; 1,6,7,8-Tetrahydroxyoctahydroindolizine; 6,7-Diepicastanospermine
生化机理 Castanospermine, originally derived from Castanosperum australe has been shown to be a potent inhibitor of almond emulsion β-glucosidase, and also to inhibit fungal β-xylosidase. Other studies show castanospermine to have the capacity to make viral glycopeptides more susceptible to enzyme treatment. Additionally, castanospermine may have the potential ability to inhibit syncytium formation between HIV-infected and CD4-expressing cells and may also interfere with infectivity. It has also been demonstrated that this agent inhibits inflammation at the level of leukocyte extravasation in rat models of experimental adjuvant-induced arthritis and autoimmune encephalomyelitis. Castanospermine is an inhibitor of Glucosidase I, Maltase-glucoamylase, and MANBA.
应用 A glycosidase inhibitor and antiinflammatory agent.

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