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名称: Clarithromycin英文名称: Clarithromycin≥98%产品编号 C129746
CAS号: 81103-11-9分子式 C38H69NO13分子量747.95
MDL号 MFCD00865140
标识符号 | GHS07 |
信号词 | Warning |
危害声明 | H302 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
RTECS | KF4997000 |
WGK德国 | 3 |
旋光率 | -92°C |
熔点 | 225°C |
溶解性 | Soluble in ethanol ( |
存贮条件 | 储存温度 2-8°C |
产品介绍 | Clarithromycin 是一种大环内酯类抗生素,是CYP3A4抑制剂。 |
别名 | 克拉仙;克拉霉素;甲氧基红霉素;Biaxin; Biaxin XL; Clarosip; Klaricid; Cyllind;6-O-Methylerythromycin; A-56268; TE-03 |
生化机理 | Clarithromycin is a 14-member ring macrolide antibiotic and 6-O-methyl derivative of erythromycin. Clarithromycin has reported bacteriostatic action against gram-positive bacteria and some gram-negative bacteria including anaerobes. Similar to other macrolide antibiotics, this antibiotic is believed to function via binding of the ribosome within the microorganism. Studies have noted that Clarithromycin appears to bind specifically to the 50S ribosomal subunit, thus inhibiting DNA translation and inhibiting bacterial growth. This compound is both a substrate and inhibitor of CYP3A4. |
备注 | Clarithromycin (Biaxin, Klacid) is a macrolide antibiotic and a CYP3A4 inhibitor. |
应用 | A macrolide antibiotic and protein synthesis inhibitor |
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