41294-56-8阿法骨化醇

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  • 商品名称:41294-56-8阿法骨化醇
  • 商品毛重:
  • 单位:件
  • 上架时间:2017-10-31 22:39:33

名称: 阿法骨化醇英文名称: Alfacalcidol97%产品编号 A120129
CAS号: 41294-56-8分子式 C27H44O2分子量400.64
Beilstein号 EC号 255-297-1MDL号 MFCD00868328PubChem编号 24850815

标识符号 GHS06GHS06
信号词 Danger
风险声明 (欧洲) R26/27/28
安全声明(欧洲) S28;S36/37;S45
警示性声明 P260,P264,P280,P284,P302+P350,P310
危害码(欧洲) T+
危害声明 H300,H310,H330
个人防护设备 Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges
RTECS VS2851000
WGK德国 3

属性

存贮条件 储存温度-20°C

描述

别名 ;1α-Hydroxycholecalciferol, Alfacalcidol 1α-Hydroxyvitamin D3
生化机理 Synthetic vitamin D3 analog that is metabolized to 1,25-dihydroxycholecalcif?erol. Inhibits bone resorption and stimulates bone formation. Supresses parathyroid hormone secretion by bovine parathyroid cells. Cholecalciferol is an inactive form of vitamin D3 which undergoes various levels of hydroxylation to form active vitamin D3 analogs. 1α-Hydroxyvitamin D3 (alfacalcidol is a synthetic analog that is metabolized to 1,25-dihydroxycholecalcif?erol, the biologically active form of vitamin D3 in calcium absorption and deposition. 1α,25-Dihydroxyvitamin D3 has widespread effects on cellular differentiation and proliferation, and can modulate immune responsiveness, and central nervous system function. Recent studies suggest that 1α,25-dihydroxyvitamin D3 acts as a chemopreventive agent against several malignancies including cancers of the prostate and colon and shows synergy with other anticancer compounds.
备注 本产品只用于科研之用。

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